Large Incisional Hernia & Ehlers Danlos Syndrome

Do you really have Ehlers-Danlos syndrome? If so, what type?
In my experience, the best repair is a primary closure with very wide synthetic mesh implantation, even a sandwich repair, as most patients with EDS dehisce from a minimalist approach. Also, I would try not to do a component separation, if possible. One consideration is Botox injection. This is because the released tissue will then bulge out from the component separation and that is a much more difficult problem to treat and also a very ugly outcome.