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I believe Dr. Felix said his initial tissue repairs lasted him 20-25 years. He got them when he was younger and likely a good weight. I am sure a lot goes into how long they last. Weight, age, activity level, overall tissue health, quality and type of repair. I know my grandfather got a tissue repair in the late 70’s or early 80’s when he was in his mid to late 50’s possibly. As far as I know it lasted him the remainder of his days (lived to 91) but can’t say for sure as we never talked about it. If he had a recurrence in his very old age he probably wasn’t bothered by it and didn’t mention it.